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COMPLEMENT C5 CONVERTASE, ALTERNATIVE PATHWAY
Descriptors Found:
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DeCS
Descriptor
English
:
Complement C5 Convertase, Alternative Pathway
Descriptor
Spanish
:
C5 Convertasa de la Vía Alternativa del Complemento
Descriptor
Portuguese
:
C5 Convertase da Via Alternativa do Complemento
Synonyms
English
:
Alternative Pathway C5 Convertase
C5 Convertase (C3bBb3b)
C5 Convertase, Alternative Pathway
Tree Number:
D12.776.124.486.274.045.387.500.750
Definition
English
:
A
serine
protease that cleaves multiple
COMPLEMENT C5
into
COMPLEMENT C5A
(
anaphylatoxin
) and
COMPLEMENT C5B
in the ALTERNATIVE
COMPLEMENT ACTIVATION
PATHWAY. It is the complex of ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) with an additional
COMPLEMENT C3B
, or C3bBb3b.
Pharmacological Action:
Immunologic Factors
History Note
English
:
2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50831
Unique Identifier:
D051566
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS